Toxic Bacteria Devours Tumors With Precision

A bacterium found in soil that can cause flesh-ravaging infections in its natural state has been converted — with a few genetic tweaks — into a precise tumor assassin.

Researchers from the Johns Hopkins Kimmel Cancer Center excised the toxin-producing gene from the bacterium Clostridium novyi, which, in its natural form, can be fatal when introduced to the bloodstream. They injected spores of the modified bacteria directly into tumors of mice, dogs and ultimately a human patient. In all t

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