Could Modified Proteins Build the Microfactories of the Future?

The central production line of active biomolecules – from DNA to RNA to proteins – is an exquisitely fine-tuned process with a rich evolutionary heritage. From the four-base nucleotide alphabet, three-letter sets, or codons, specify one of 20 amino acids to build the enzymes that make metabolism happen.

There is, however, some room to maneuver, and biologists have found an important loophole to hack the system and introduce novel functions or sensing capabilities into different proteins.

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